Muscle cramps and weakness secondary to graft versus host disease fasciitis

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Muscle cramps and weakness secondary to graft versus host disease fasciitis.

Sir, Uncommon manifestations of chronic graft versus host disease (GvHD) include a variety of neurological presentations (Bolger et al., 1986; Urbano-Marquez et al., 1986; Nelson and McQuillen, 1988; Tse et al., 1999; Takahashi et al., 2000; Ma et al., 2002; Nagashima et al., 2002) and sclerodermatous skin changes (Shulman et al., 1978; Chosidow et al., 1992; Janin et al., 1994; Penas et al., 2...

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Case report Myositis associated graft-versus-host-disease presenting as respiratory muscle weakness

Myositis associated with graft-versus-hostdisease (GVHD) typically presents with proximal muscle weakness, myalgias, and a raised creatinine phosphokinase (CPK) level. We report a case of a 51 year old man who developed respiratory muscle weakness five years after an allogeneic bone marrow transplant for multiple myeloma. His symptoms included tachypnoea, abdominal paradox, and orthopnoea. Pulm...

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Myositis associated graft-versus-host-disease presenting as respiratory muscle weakness.

Myositis associated with graft-versus-host-disease (GVHD) typically presents with proximal muscle weakness, myalgias, and a raised creatinine phosphokinase (CPK) level. We report a case of a 51 year old man who developed respiratory muscle weakness five years after an allogeneic bone marrow transplant for multiple myeloma. His symptoms included tachypnoea, abdominal paradox, and orthopnoea. Pul...

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Muscle Cramps and Neuropathies in Patients with Allogeneic Hematopoietic Stem Cell Transplantation and Graft-versus-Host Disease

OBJECTIVE Graft-versus-host disease (GVHD) is an immune-mediated multisystemic disorder and the leading cause of morbidity after allogeneic hematopoietic stem cell transplantation. Peripheral nervous system manifestations of GVHD are rare but often disabling. Whereas immune-mediated neuropathies are an established feature of GVHD, muscle cramps are not well characterized. METHODS In a single-...

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Graft Versus Host Disease

Commonly referred to as GVHD, graft-versus-host disease is a man-made condition that arises when patients are transplanted with donor tissue that is not identical to their own. Transplants from other individuals are called allogeneic (‘allo’ meaning ‘other’ and ‘geneic’ referring to ‘genes’). GVHD occurs after hematopoietic stem cell or bone marrow transplantation but is most commonly experienc...

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ژورنال

عنوان ژورنال: European Journal of Neurology

سال: 2005

ISSN: 1351-5101,1468-1331

DOI: 10.1111/j.1468-1331.2004.00964.x